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There was a time when operations were done without the use of anesthesia. Now the medical field is getting innovative with new discoveries. Hence anesthesia is a crucial element of any surgery. Anesthesia is administered to patients to provide them relief from pain. Today based on the patient age, sex and condition the anesthesia drugs are administered to the patient. There are various types of anesthesia and various medical professions that are able to administer anesthesia. If anesthesia Is not administered to patient in the right proportion it can cause fatal side effects. Anesthesia offers instant pain relief during operations and surgeries.
The exact mechanisms that cause anesthesia are not well known. It makes certain proteins expand. General anesthesia drugs range from simplicity of alcohol to complexity of sevoflurane
There are three types of anesthesia
Local anesthesia is given before minor surgeries. This reduces pain sensations in small, focused areas of the body, but the person receiving the treatment remains conscious.
Regional anesthesia numbs an entire portion of the body - the lower half, for example, during childbirth. There are two main forms of regional anesthesia: Spinal anesthetic and epidural anesthetic.
Spinal anesthetic is used for surgeries of the lower limbs and abdomen. This is injected into the lower back and numbs the lower body. Epidural anesthesia is often used to reduce the pain of childbirth and lower limb surgery.
General anesthetics are known to act at a number of sites within the central nervous system (CNS). The importance of these sites on the induction of anesthesia is not fully understood but they include:
There are multiple sites that general anesthetics can work at in the brain.
• Cerebral cortex: The brain's outer layer involved in tasks relating to memory, attention, perception among other functions
• Thalamus: Its roles include relaying information from the senses to the cerebral cortex and regulating sleep, wakefulness, and consciousness.
• Reticular activating system: Important in regulating sleep-wake cycles
• Spinal cord: Passes information from the brain to the body and vice versa. It also houses circuitry that controls reflexes and other motor patterns.

Anesthesia covers a wide range of sedation, local anesthesia, epidural anesthesia, pediatric anesthesia, spinal anesthesia, critical care, surgical anesthesia, general anesthesia and many more, going through the Annals of Anesthesia and Pain Medicine will help the doctors in measuring the right dose and attain the desired impact.
These journals help us in knowing the latest developments in the medical field. The anesthesia field is constantly evolving. Hence these journals help us keep abreast of advances in medical field.
The publication of journal "Annals of Anesthesia and Pain Medicine" is done after thorough quality check and hence the authenticity of the documents cannot be questioned. The scripts are reviewed by a panel of experts and only after approval from editor it is finally accepted and published.

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